Complex In Vitro Models

Now at WaveCyte BioLabs: Complex In Vitro Models (CIVM)

Recreate the complexity of the human immune microenvironment using customizable, donor-matched systems. WaveCyte BioLabs combines primary immune cells with relevant target and support cell types to model immune activation, suppression, and drug response in vitro.

Built for immunotherapy screening, cytokine risk assessment, and mechanistic validation. Translational by design

• Redefine Immune Therapy Testing – Replace animal models with human-relevant platforms that integrate immune cells, disease-relevant targets and tissue-specific components

• Seamless Integration into Downstream Studies – Cytokine release, immune-mediated killing, checkpoint blockade, microenvironmental suppression and more

• Customizable Models – Model complexities tailored to your specific assays.

• Faster Turnaround – High quality results delivered quickly

CIVM Related Services

Matched Immune Cell Subsets

On-demand multiple purified donor-matched immune cell types, to maintain biological context and reduce variability. Fresh or cryopreserved

Configure models to assess tumor cell killing, activation thresholds and immunosuppression using LDH release, cytokine profiling (MSD) and flow cytometry.

Recreate disease relevant architecture by combining targets with fibroblasts, epithelial, endothelial and stromal cells to mimic human microenvironment

Functional Cytotoxicity & Activation Assays

Custom Microenvironments

Model checkpoint inhibitors, bispecifics and cell therapies using customizable human-based systems designed to reflect clinical mechanisms

Translational Immunotherapy Models

Donor Consistency & HLA Matching

Support reproducibility with same-donor immune cells available fresh or cryopreserved. Optional HLA typing to support longitudinal and regulatory-aligned workflows

Mechanism-Driven Study Design

Design models aligned with your drug's biology and target pathway, tailored for translational and regulatory relevance from early discovery to IND-enabling studies

We help you model the complexity that matters, with the flexibility to adapt to any mechanism

Need a research partner who moves at your speed? Let’s talk. WaveCyte BioLabs: Science Without the Slowdown.