Pharmacokinetic & Toxicokinetic Analysis

Comprehensive Pharmacokinetics (PK) and Toxicokinetics (TK) analysis is essential for evaluating the behavior of pharmaceutical compounds within the body. At WaveCyte BioLabs, we provide rigorous and scientifically robust assay to support pre-clinical and clinical studies with precise measurement of drug exposure and metabolism

Our PK & TK Analysis Services

• ADME Profiling: Detailed analysis of drug absorption, distribution, metabolism, and excretion characteristics in preclinical and clinical studies.

• Drug and Metabolite Profiling: Identification of drug metabolites and the assessment of their potential toxicity or activity, helping to understand the pharmacological effects of different forms of the drug.

• PK and PD Modeling: Population PK/PD modeling and simulation to predict drug concentrations and effect in various patient populations, informing dosing strategies and safety margins.

• Dose-Response Studies: Evaluation of the relationship between administered dose and pharmacokinetic parameters to guide dose selection.

• Toxicity Testing and Safety Pharmacology: Conducting studies to determine toxicological effects at different exposure levels and predict the safety of compounds under long-term exposure scenarios.

• Comprehensive Bioinformatics integration: Advanced bioinformatics tools and data analytics to interpret complex PK/PD data, enabling actionable insights and streamlined decision-making during drug development.

What Is Toxicokinetics (TK)

Pharmacokinetics is the study of how drugs are absorbed, distributed, metabolized, and excreted in the body (ADME). Understanding these processes is key to optimizing drug formulations, dosing regimens, and therapeutic efficacy. Our PK services assess the movement of drugs over time to support the development of safe and effective treatments.

Toxicokinetics focuses on how toxic substances—whether therapeutic agents at high doses, environmental toxins, or industrial chemicals—are absorbed, distributed, metabolized, and eliminated by the body. By studying the toxicokinetics, we provide insight into the potential adverse effects of compounds, helping to predict and prevent toxicity at varying exposure levels.

What Is Pharmacokinetics (PK)

Precise, reliable measurement of drug absorption, distribution, metabolism, and excretion (ADME) at every stage of drug development. Utilizing LC-MS/MS, immunoassays, and HPLC, we ensure accurate quantification of drug compounds. With integrated PK/PD modeling, dose-response studies, and advanced bioinformatics, we deliver actionable insights into drug behavior in vivo.

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