Protein Characterization

Accurate protein characterization is critical for understanding protein structure, function, and stability. At WaveCyte BioLabs, we provide comprehensive protein characterization services to ensure the quality and functionality of your proteins for research, development, and manufacturing purposes.

Our Protein Characterization Services

Structural Analysis

• SDS-PAGE and Western Blotting: Confirm protein size and identity.

• Mass Spectrometry: Determine molecular weight and post-translational modifications.

Functional Characterization

• Enzyme Activity Assays: Verify biological activity.

• SPR and BLI Binding kinetics: Assess interactions with biomolecules including affinity, binding rates and dissociation constants

Biophysical Analysis

• Circular Dichroism (CD) Spectroscopy: Evaluate protein folding and secondary structure.

• Dynamic Light Scattering (DLS): Measure protein size and aggregation.

Stability Studies

• Thermal Stability Assays: Assess protein behavior under varying temperatures.

• Shelf-Life Testing: Evaluate long-term stability under storage conditions.

Purity and Homogeneity Assessment: High-performance liquid chromatography (HPLC) and size-exclusion chromatography (SEC) to ensure sample purity and uniformity.

What Is Protein Characterization

Protein characterization involves a series of analytical techniques used to evaluate the physical, chemical, and functional properties of proteins. This ensures that proteins meet quality standards and perform as intended in their applications.

Precise protein characterization at every stage of drug development. Using SPR and BLI for real-time binding kinetics, along with mass spectrometry and Circular Dichroism (CD) for impurity profiling and structural analysis, we provide valuable insights into the structural and functional properties of therapeutic proteins. Our services are crucial for monoclonal antibodies, biosimilars, and novel protein therapeutics.

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